Evaluation of Parabens and Bisphenol A Concentration Levels in Wild Bat Guano Samples
Abstract
:1. Introduction
2. Materials and Methods
2.1. Reagents
2.2. Sample Collection
2.3. Sample Treatment
2.4. Method Validation, Quality Assurance and Quality Control
2.5. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Compound | Linearity | MDL | MQL | RSD | Rec |
---|---|---|---|---|---|
R2 | (ng/g dw) | (ng/g dw) | (%) | (%) | |
MeP | 0.998 | 0.02 | 0.05 | 12.1 | 98.6 |
EtP | 0.998 | 0.02 | 0.05 | 11.2 | 108.1 |
PrP | 0.999 | 0.02 | 0.05 | 14.2 | 107.2 |
BuP | 0.998 | 0.02 | 0.05 | 9.5 | 118.8 |
BPA | 0.997 | 2.00 | 5.00 | 35.9 | 139.3 |
Bat Colony No. | Sample No. | Concentration (ng/g) | ||||
---|---|---|---|---|---|---|
MeP | EtP | PrP | BuP | BPA | ||
1 | 1 | 31.1 | 0.68 | 0.41 | <MDL | <MDL |
2 | 25.5 | 0.65 | 0.30 | <MDL | <MDL | |
3 | 27.8 | 0.75 | 0.48 | <MDL | <MDL | |
4 | 20.7 | 0.23 | 0.08 | <MDL | <MDL | |
5 | 52.7 | 35.3 | 18.6 | <MDL | <MDL | |
6 | 25.1 | 1.48 | 0.81 | <MDL | <MDL | |
7 | 25.6 | 1.89 | 2.09 | <MDL | <MDL | |
8 | 56.1 | 55.3 | 46.4 | 3.61 | <MDL | |
9 | 142 | 239 | 229 | 27.5 | <MQL | |
10 | 26.9 | 3.48 | 4.38 | <MDL | <MDL | |
2 | 1 | 33.6 | 2.27 | 2.59 | <MDL | <MDL |
2 | 50.3 | 1.73 | 1.51 | <MDL | <MDL | |
3 | 60.4 | 2.38 | 1.59 | <MDL | <MDL | |
4 | 43.8 | 0.95 | 0.99 | <MDL | <MDL | |
5 | 35.9 | 0.60 | 0.42 | <MDL | <MDL | |
6 | 40.6 | 0.41 | <MQL | <MDL | <MDL | |
7 | 38.6 | 0.55 | <MQL | <MDL | <MDL | |
8 | 35.9 | 0.46 | <MQL | <MDL | <MDL | |
9 | 37.2 | 0.67 | <MQL | <MDL | <MDL | |
10 | 43.7 | <MQL | <MQL | <MDL | <MDL | |
3 | 1 | 70.2 | 1.60 | 1.33 | <MDL | <MDL |
2 | 72.7 | 0.92 | <MQL | <MDL | <MDL | |
3 | 46.6 | <MQL | <MQL | <MDL | <MDL | |
4 | 80.3 | 0.84 | <MQL | <MDL | <MDL | |
5 | 73.5 | 1.07 | <MQL | <MDL | <MDL | |
6 | 96.4 | <MQL | <MQL | <MDL | <MDL | |
7 | 86.4 | <MQL | <MQL | <MDL | <MDL | |
8 | 100 | 1.28 | 1.34 | <MDL | <MDL | |
9 | 71.2 | <MQL | <MQL | <MDL | <MDL | |
10 | 119 | 0.70 | <MQL | <MDL | <MDL | |
4 | 1 | 50.8 | <MQL | <MQL | <MDL | <MDL |
2 | 24.4 | <MQL | <MQL | <MDL | <MDL | |
3 | 14.0 | <MQL | <MQL | <MDL | <MDL | |
4 | 22.6 | <MQL | <MQL | <MDL | <MDL | |
5 | 22.9 | <MQL | <MQL | <MDL | <MDL | |
6 | 24.2 | <MQL | <MQL | <MDL | <MDL | |
7 | 24.4 | <MQL | <MQL | <MDL | <MDL | |
8 | 25.4 | <MQL | <MQL | <MDL | <MDL | |
9 | 45.3 | <MQL | <MQL | <MDL | <MDL | |
10 | 24.3 | <MQL | <MQL | <MDL | <MDL |
Compound | Range (ng/g) | Arithmetic Mean | Geometric Mean | Median | Frequency of Detection above MQL |
---|---|---|---|---|---|
MeP | 14.00–142.00 | 48.70 | 41.81 | 39.6 | 100 |
EtP | <0.05–239 | 14.21 | 1.61 | 0.95 | 62.5 |
PrP | <0.05–229 | 18.37 | 1.78 | 1.45 | 42.5 |
BuP | <0.02–27.5 | 15.56 | 9.96 | 15.56 | 5 |
BPA | <2.00–<5.00 | - | - | - | 0 |
Bat Colony Number | 1 | 2 | 3 | 4 |
---|---|---|---|---|
MeP | ||||
Number of samples, in which levels were higher than MQL | 10 | 10 | 10 | 10 |
Minimum | 20.70 | 33.60 | 46.60 | 14.00 |
Maximum | 142 | 60.40 | 119 | 50.80 |
Mean ± SD | 43.35 ± 36.7 A | 42.00 ± 8.13 | 81.63 ± 19.97 AB | 27.83 ± 11.21 B |
EtP | ||||
Number of samples in which levels were higher than MQL | 10 | 9 | 6 | 0 |
Minimum | 0.23 | 0.41 | 0.7 | - |
Maximum | 239 | 1.97 | 1.6 | - |
Mean ± SD | 33.88 ± 74.51 | 1.11 ± 0.79 | 1.07 ± 0.33 | - |
PrP | ||||
Number of samples in which levels were higher than MQL | 10 | 5 | 2 | 0 |
Minimum | 0.08 | 0.42 | 1.33 | - |
Maximum | 229 | 2.17 | 1.34 | - |
Mean ± SD | 30.26 ± 71.34 | 1.42 ± 0.8 | 1335 ± 0.01 | - |
BuP | ||||
Number of samples in which levels were higher than MDL | 2 | 0 | 0 | 0 |
Minimum | 3.61 | - | - | - |
Maximum | 27.5 | - | - | - |
Mean ± SD | 15.56 ± 16.89 | - | - | - |
BPA | ||||
Number of samples in which levels were higher than MQL | 0 | 0 | 0 | 0 |
Minimum | - | - | - | - |
Maximum | - | - | - | - |
Mean ± SD | - | - | - | - |
Species | Localization | Matrix | n | Concentration Levels | Ref. | |||
---|---|---|---|---|---|---|---|---|
MeP | EtP | PrP | BuP | |||||
Dolphin (various species) | Gulf of Mexico, Florida (USA) | liver | 17 | <41.1–865 | n.d. | <2.05–3.47 | n.d. | [39] |
blubber | 17 | n.a.–<8.21 | n.d. | n.d. | n.d. | |||
Pygmy sperm whale | Atlantic ocean/Anciote river | liver | 3 | <20.5–37.7 | n.d. | <4.10 | n.d. | |
blubber | 3 | n.a. | n.d. | n.d. | n.d. | |||
Sea otter | California Coast (USA) | liver | 25 | n.a.–126 | <4.1–11.8 | <1.03–3.95 | n.d. | |
kidney | 10 | n.a.–360 | n.d. | n.d. | n.d. | |||
brain | 10 | 5.99–77.2 | <1.03–3.26 | n.d. | n.d. | |||
Washington Coast (USA) | liver | 18 | <20.5–358 | n.d. | n.d. | <4.1–31.8 | ||
Northern sea otter | Alaskan Coast (USA) | liver | 14 | n.a.–686 | <8.21–31.6 | n.d. | n.d. | |
Polar bear | Alaska (USA) | liver | 10 | <4.10–16.9 | n.d. | n.d. | n.d. | |
Common dolphin | Korean coastal waters | blubber | 6 | 1.3–7.9 | [40] | |||
muscle | 6 | 13–121 | ||||||
melon | 6 | 4.8–12 | ||||||
stomach | 6 | 44–118 | ||||||
liver | 6 | 13–224 | ||||||
testis/ ovary | 6 | 26–76 | ||||||
brain | 5 | 4.2–50 | ||||||
uterus | 2 | 37–74 | ||||||
Finless porpoises | Korean coastal waters | blubber | 6 | 6.4–21 | ||||
muscle | 6 | 12–88 | ||||||
melon | 6 | 21–71 | ||||||
stomach | 6 | 75–228 | ||||||
kidney | 6 | 181–359 | ||||||
liver | 6 | 235–569 | ||||||
testis/ovary | 6 | 44.3–256 | ||||||
stomach content | 2 | 59–76 | ||||||
Fish (various species) | Greater Pittsburgh Area (USA) | brain | 58 | n.d. | n.d. | n.d. | n.d. | [41] |
Fish (various species | Taihu Lake (China) | muscle | 199 | 88.1–1200 | 33.6–450 | 55.3–543 | <LOQ–40.0 | [57] |
Fish and bivalves (various species) | Atlantic ocean, pacific Ocean, Mediterranean Sea, Victoria lake (Uganda) | body | 64 | 0.8–32 | n.d. | n.d. | n.d. | [58] |
Fish (various species) | New York State (USA) | muscle | 50 | n.a.−690 | n.d. | n.d. | n.d. | [42] |
Fish (various species) | Florida (USA) | liver | 6 | <2.01–44.3 | n.d. | n.d. | n.d. | |
muscle | 6 | n.a.–43.9 | n.d. | n.d. | n.d. | |||
kidney | 1 | 18.8 | n.d. | n.d. | n.d. | |||
gill | 1 | 71 | n.d. | n.d. | n.d. | |||
brain | 1 | 735 | n.d. | n.d. | n.d. | |||
Black bear | Michigan (USA) | liver | 2 | 33.5–58.2 | n.d. | n.d. | n.d. | |
kidney | 2 | 24.0–37.6 | n.d. | n.d. | n.d. | |||
Sea eagle | Baltic Sea area | liver | 20 | <8.01–657 | n.d. | n.d. | n.d. | |
Albatrosses (various species) | Sand Island, Midway (USA) | liver | 15 | <8.01–23.4 | n.d. | n.d. | n.d. | |
kidney | 16 | <8.01–18.2 | n.d. | n.d. | n.d. | |||
brain | 12 | <1.99–6.66 | n.d. | n.d. | n.d. | |||
fat | 10 | n.a. | n.d. | n.d. | n.d. | |||
muscle | 12 | <2.01–15.7 | n.d. | n.d. | n.d. | |||
eggs | 13 | n.a. | n.d. | n.d. | n.d. | |||
Bald eagle | Michigan (USA) | liver | 1 | 796 | n.d. | n.d. | n.d. | |
plasma | 15 | <0.2–0.37 | n.d. | n.d. | n.d. | |||
kidney | 1 | 580 | n.d. | n.d. | n.d. | |||
muscle | 2 | 87.4–169 | n.d. | n.d. | n.d. | |||
Herring gull | Michigan (USA) | eggs | 9 | <1.99–14.0 | n.d. | n.d. | n.d. | |
Common cormorant | Michigan USA) | eggs | 4 | n.a. | n.d. | n.d. | n.d. | |
Loon | Carteret County (USA) | liver | 10 | <8.01–336 | n.d. | n.d. | n.d. | |
Loon | Maine and New Hampshire (USA) | eggs | 15 | <1.99–22.2 | n.d. | n.d. | n.d. | |
Fish (various species) | Yangtze river (China) | plasma | 36 | 11.6–39.5 | 0–10.5 | 0–6.97 | 0–b1.46 | [38] |
Fish (various species) | Yangtze river (China) | bile | 35 | 8.17–21.9 | 0–31.6 | 2.19–112 | 0–4.42 | [59] |
Fish (various species) | Spain/various rivers | muscle | 59 | n.d.–84.69 | n.d.–0.82 | n.d.–7.43 | [60] | |
Striped Catfish | Colombia/various rivers | muscle | 20 | <20–32.0 | [61] | |||
Clams | Antarctica | body | 7 | <2.1–5.8 | n.d. | n.d.–5.3 | n.d. | [62] |
Sea urchin | body | 1 | 5.7 | n.d. | n.d. | n.d. | ||
Fish (Emerald rockcod) | body | 7 | 5.1–26.9 | n.d. | n.d | n.d. | ||
liver | 1 | 2.4 | n.d. | n.d. | n.d. |
Matrix | n | BPA Concentration | References |
---|---|---|---|
Human hair | 42 | 26.1–1498.6 | [34] |
20 | 3.6–52.9 | [69] | |
Human blood serum | 155 | 0.11–112.1 | [70] |
245 | 0.05–4.017 | [71] | |
40 | 4.4–55.1 | [72] | |
52 | 4.3–55.3 | [73] | |
Human breast milk | 20 | 0.09–11.56 | [74] |
Human urine | 250 | 0.05–53.1 | [75] |
Seal blood serum | 108 | <LOQ–81.58 | [76] |
Seal milk | 44 | 0.1–406 | [76] |
Seal fur | 17 | <LOQ–137.2 | [34] |
Seal feces | 60 | 20.06–75,659.78 | [36] |
Dog fur | 30 | <MDL–436 | [32] |
Pig muscles | 5 | 13.77–49.86 | [33] |
Water bird whole body | 10 | 19.7–440.1 | [77] |
Water bird feather | 26 | 29.3–512.4 | [34] |
Water bird intestine | 52 | 6.6–1176.2 | [78] |
Water bird blood | 53 | <0.07–30.6 | [78] |
Water bird lungs | 53 | <2.0–331.7 | [78] |
Water bird guano | 7 | 41.6–2701.9 | [77] |
30 | 41.85–1666.54 | [36] | |
Sea fish muscles | 12 | 25.4–798.4 | [77] |
Sea mussels | 10 | 6.8–197.2 | [77] |
148 | Nd–273.6 | [79] | |
Sea zooplankton | 5 | 105.7–769.2 | [77] |
Sea water | 120 | <LOQ–0.2779 | [80] |
71 | 0.00377–0.82271 | [36] | |
Inland surface water | 105 | NQ–0.095 | [63] |
Sea sediment | 72 | 0.08–26.39 | [36] |
Beach sand | 71 | 0.83–15.80 | [36] |
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Gonkowski, S.; Martín, J.; Aparicio, I.; Santos, J.L.; Alonso, E.; Rytel, L. Evaluation of Parabens and Bisphenol A Concentration Levels in Wild Bat Guano Samples. Int. J. Environ. Res. Public Health 2023, 20, 1928. https://doi.org/10.3390/ijerph20031928
Gonkowski S, Martín J, Aparicio I, Santos JL, Alonso E, Rytel L. Evaluation of Parabens and Bisphenol A Concentration Levels in Wild Bat Guano Samples. International Journal of Environmental Research and Public Health. 2023; 20(3):1928. https://doi.org/10.3390/ijerph20031928
Chicago/Turabian StyleGonkowski, Slawomir, Julia Martín, Irene Aparicio, Juan Luis Santos, Esteban Alonso, and Liliana Rytel. 2023. "Evaluation of Parabens and Bisphenol A Concentration Levels in Wild Bat Guano Samples" International Journal of Environmental Research and Public Health 20, no. 3: 1928. https://doi.org/10.3390/ijerph20031928